Inflammation in bipolar affective disorder patients who committed or did not commit a crime: neutrophil/lymphocyte, platelet/lymphocyte, monocyte/lymphocyte ratios and mean platelet volume

The aim of the study is to investigate the inflammation markers in bipolar affective disorder(BAD) patients who were involved in crime or did not involve in crime. It was aimed to evaluate the neutrophil/lymphocyte ratios (NLR), platelet/lymphocyte ratios (PLR), monocyte/lymphocyte ratios (MLR) and...

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Bibliographic Details
Main Author: Özsoy, Filiz (Author)
Contributors: Ünal Demir, Figen ; Taşcı, Gülay
Format: Electronic Article
Language:English
Published: 2021
In: The journal of forensic psychiatry & psychology
Year: 2021, Volume: 32, Issue: 4, Pages: 575-586
Online Access: Volltext (lizenzpflichtig)
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Keywords:
monocyte/lymphocyte ratio
platelet/lymphocyte ratios
neutrophil/lymphocyte ratios
Crime
inflammation
Bipolar affective disorder
Description
Summary:The aim of the study is to investigate the inflammation markers in bipolar affective disorder(BAD) patients who were involved in crime or did not involve in crime. It was aimed to evaluate the neutrophil/lymphocyte ratios (NLR), platelet/lymphocyte ratios (PLR), monocyte/lymphocyte ratios (MLR) and platelete distribution width (RDW) by comparing with controls and each other. 272 individuals were included in our study; patients diagnosed with BAD (100 committed a crime, 72 has no criminal history) in the patient group and 100 individuals in the control. The hemoglobin, hematocrit and PDW levels were found higher in the group involved in crime than the group not involved in crime as well as controls. Also, hemoglobin, hematocrit, WBC, RBC, PDW, neutrophil, monocyte values were found higher in the patients involved in crime than the patients not involved in crime. NLR, PLR and MLR were found low in both patient groups compared to controls. Based on our results; some inflammatory parameters were different in the patients involved in crime than the group not involved in crime and healthy controls. To generalize the findings of our study and to make them significant, prospective studies should be conducted with larger sample groups and people with different disorders.
ISSN:1478-9957
DOI:10.1080/14789949.2020.1870708