A virtual-reality based intervention on thoughts of the future self to reduce negative afect, depression, and suicidal ideation: protocol for a feasibility and acceptability randomized controlled pilot trial (FutureU for Mental Health)

Background: Thinking about the future in a clear and detailed way is critical to daily life, generating meaning, motivation, and well-being overall. In depression and suicidal ideation (SI), executive functioning defcits can make future-oriented thinking (FT) particularly efortful. Many intervention...

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Autores principales: Webb, Margaret A. (Autor) ; Gelder, Jean-Louis van (Autor)
Tipo de documento: Electrónico Artículo
Lenguaje:Inglés
Publicado: 2025
En: Pilot and feasibility studies
Año: 2025, Volumen: 11, Páginas: 1-20
Acceso en línea: Volltext (kostenfrei)
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245 1 2 |a A virtual-reality based intervention on thoughts of the future self to reduce negative afect, depression, and suicidal ideation  |b protocol for a feasibility and acceptability randomized controlled pilot trial (FutureU for Mental Health)  |c Margaret A. Webb and Jean‑Louis van Gelder 
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520 |a Background: Thinking about the future in a clear and detailed way is critical to daily life, generating meaning, motivation, and well-being overall. In depression and suicidal ideation (SI), executive functioning defcits can make future-oriented thinking (FT) particularly efortful. Many interventions address the quality of future thinking in depression and SI but are limited by the thoughts that a person can generate on their own. Finding ways to intervene on FT that do not rely fully on the overburdened cognitive processes of a person experiencing depression or SI may improve the efcacy of these interventions. The present pilot RCT investigates the feasibility, acceptability, and proof of concept for a novel virtual-reality (VR)-based intervention on thoughts of the future self (FutureU for Mental Health; FU-MH) to improve a person’s ability to think about the future and to reduce symptoms of depression and SI. Methods: Using a 4-month, randomized, controlled, participant-blind, add-on superiority trial with three parallel groups, we will evaluate the potential of a two-part VR-based intervention on thoughts of the future and the future self to reduce negative afect and depressive symptoms. We aim to recruit 60 participants and randomize them to either a control group, treatment group A, or treatment group B, where treatment groups are exactly the same with the exception of the order of presentation for intervention parts. Feasibility will be measured in terms of enrollment and retention, as well as subjective measures of participant engagement and embodiment in VR. Acceptability will be measured through participant self-report. Proof of concept will be evaluated through the demonstration of the intended efect on targeted cognitive mechanisms, evidence of improvement in clinical outcomes, and evidence of efcacy among those with cognitive processing defcits. Discussion: This study will provide valuable direction for further iterations of FutureU for Mental Health and a larger scale clinical trial. Implications of hypothesized outcomes include support for a novel intervention on thoughts of the future self in depression and SI, and VR as a novel medium of intervention and prevention in depression and SI. 
650 4 |a Virtual reality (VR) 
650 4 |a Intervention 
650 4 |a Depression 
650 4 |a Suicidal Ideation 
650 4 |a Episodic future thinking 
650 4 |a Future self 
700 1 |a Gelder, Jean-Louis van  |e VerfasserIn  |0 (DE-588)1045393959  |0 (DE-627)774480106  |0 (DE-576)370631609  |4 aut 
773 0 8 |i Enthalten in  |t Pilot and feasibility studies  |d London : BioMed Central, 2015  |g 11(2025), Artikel-ID 143, Seite 1-20  |h Online-Ressource  |w (DE-627)818042532  |w (DE-600)2809935-7  |w (DE-576)42618291X  |x 2055-5784  |7 nnas 
773 1 8 |g volume:11  |g year:2025  |g elocationid:143  |g pages:1-20 
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