RT Book T1 Psychophysiological activity and reactivity in children and adolescents with conduct problems:A systematic review and meta-analysis A1 Bobak, Billy A2 Zhang, Junhua A2 Kyranides, Melina Nicole A2 Goodwin, Daniel A2 Goble, Poppy A2 Fanti, Kostas A. A2 Eisenbarth, Hedwig A2 Demetriou, Chara A. A2 Cortese, Samuele LA English YR 2019 UL https://krimdok.uni-tuebingen.de/Record/1866606719 AB The aim of this study was to conduct a systematic review of the literature and meta-analysis to estimate the association between psychophysiological activity and reactivity at baseline or after a psychological task with conduct problems (CP) among children and adolescents. We systematically reviewed published studies reporting autonomic nervous system activity in youth with CP and meta-analyzed the relationship between CP and autonomic baseline as well as task-related reactivity in 66 studies (N = 10,227). Across 34 included case-control studies that were based on CP cut-off scores, we found a significant pooled effect for task related Skin-Conductance, Respiratory Sinus Arrhythmia, and cardiac Pre-Ejection Period, but no significant group differences for Heart Rate nor for any baseline measures. Findings suggested reduced parasympathetic and sympathetic reactivity to emotional tasks, pointing to co-inhibition of the two systems. However, across 32 studies with correlational design we only found a significant negative correlation of baseline and task-related heart rate with CP. The present meta-analysis derived several conclusions that have the potential to inform biological vulnerability models and biologically driven interventions DO 10.1016/j.neubiorev.2019.02.016