The Effect of MAOA and Stress Sensitivity on Crime and Delinquency: a Replication Study

Across several meta-analyses, MAOA-uVNTR genotype has been associated with an increased risk for antisocial behavior among males who experienced early life adversity. Subsequently, early life stress and genetic susceptibility may have long-term effects on stress sensitivity later in life. In support...

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1. VerfasserIn: Christ, Christa C. (VerfasserIn)
Beteiligte: Schwartz, Joseph A. ; Savolainen, Jukka ; Brauer, Jonathan R. ; Stoltenberg, Scott F.
Medienart: Elektronisch Aufsatz
Sprache:Englisch
Veröffentlicht: 2018
In: Journal of contemporary criminal justice
Jahr: 2018, Band: 34, Heft: 3, Seiten: 336-353
Online Zugang: Vermutlich kostenfreier Zugang
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520 |a Across several meta-analyses, MAOA-uVNTR genotype has been associated with an increased risk for antisocial behavior among males who experienced early life adversity. Subsequently, early life stress and genetic susceptibility may have long-term effects on stress sensitivity later in life. In support of this assumption, a recent study found evidence, in two independent samples, for a three-way interaction effect (cG × E × E) such that proximate stress was found to moderate the interactive effect of MAOA-uVNTR and distal stress on crime and delinquency among males. In light of recent developments in cG × E research, we attempted to replicate these findings in an independent sample of university students. Our results failed to support any cG × E or cG × E × E effects reported in the original study. Implications of a failed replication and general concerns for future cG × E research are discussed. 
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